Yes, it is possible. The routing policies which allow the same are
Round Robin: This routing policy allows you to select multiple gateways andhelps you to automatically route the SMS traffic among multiple gateways so that it’s utilized equally and optimally
Distributed: This routing policy allows you to distribute your SMS traffic among multiple gateways, it’s often used as an advanced Load balancer based on predefine percentage ratio (%) defined by you to route your SMS SMS traffic smoothly in less time.
Visit for more information: https://powersmpp.com/role-of-routing-in-smpp-which-routing-logic-your-sms-services-require/